BDBM50588747 CHEMBL5176738

SMILES CNC(=O)c1cncc(c1)-c1cnc2cc(-c3cnn(C)c3)c(OC)nn12

InChI Key InChIKey=RQGZFYTZDGTEOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588747   

TargetFibroblast growth factor receptor 3(Human)
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588747(CHEMBL5176738)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588747(CHEMBL5176738)
Affinity DataIC50: 428nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed