BDBM50588689 CHEMBL5204510

SMILES CC(C)(C)NC(=O)CN(Cc1ccc(cc1F)C(=O)NO)C(=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=GRVDCOBJGNUNNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588689   

TargetHistone deacetylase 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50588689(CHEMBL5204510)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50588689(CHEMBL5204510)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed