BDBM50588618 CHEMBL5185123

SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NCCOCCNC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c3ccc(O)c(OC)c3)C(C)C)C(=O)OCC)c2n1

InChI Key InChIKey=YREZZSNAITUJPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588618   

TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50588618(CHEMBL5185123)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB activation incubated for 18 hrs by SEAP-based spectrophotometry ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50588618(CHEMBL5185123)
Affinity DataEC50:  36nMAssay Description:Agonist activity at TLR7 in HEK-Blue hTLR7 cells assessed as increase in NFkappaB activation incubated for 18 hrs by SEAP-based spectrophotometry ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed