BDBM50588568 CHEMBL5186798

SMILES ONC(=O)CCCCC\C=C\c1csc(n1)C#C

InChI Key InChIKey=KAKCYHAHFMDCRW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50588568   

TargetHistone deacetylase 1(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 72nMAssay Description:Inhibition of full length his6/FLAG-tagged human recombinant HDAC1(1 to 482 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 120nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC2 (1 to 488 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC6 expressed inSf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 91nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged human recombinant HDAC3 (1 to 2383 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 270nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588568(CHEMBL5186798)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of full length N-terminal GST/C-terminal his-tagged human recombinant HDAC4 (627 to 1084 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed