BDBM50588565 CHEMBL5204550

SMILES ONC(=O)\C=C\c1csc(Br)n1

InChI Key InChIKey=NJCGMBWXZHLNNO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50588565   

TargetHistone deacetylase(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of HDAC in human NCI-H522 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HDAC in human HCT-116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of full length his6/FLAG-tagged human recombinant HDAC1(1 to 482 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 330nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC2 (1 to 488 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC6 expressed inSf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged human recombinant HDAC3 (1 to 2383 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588565(CHEMBL5204550)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed