BDBM50588560 CHEMBL5172507

SMILES ONC(=O)CCCCCCNC(=O)c1csc(Br)n1

InChI Key InChIKey=CMOICKYRNDPNQC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50588560   

TargetHistone deacetylase(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of HDAC in human NCI-H522 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of HDAC in human HCT-116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length his6/FLAG-tagged human recombinant HDAC1(1 to 482 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 78nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC2 (1 to 488 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC6 expressed inSf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 56nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged human recombinant HDAC3 (1 to 2383 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50588560(CHEMBL5172507)
Affinity DataIC50: 180nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed