BDBM50588237 CHEMBL5196693

SMILES CC1(CCN(CC1)C2=Nc3c(c(n[nH]3)c4cccc(c4)Cl)C(=O)N2)N

InChI Key InChIKey=HUNGUHBTUFJLAZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50588237   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50588237(CHEMBL5196693)
Affinity DataIC50: 101nMAssay Description:Inhibition of N-terminal his6-tagged wild type recombinant human SHP2 (1 to 597 residues) expressed in Escherichia coli BL21 (DE3) cells using fluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)