BDBM50587881 CHEMBL5173649

SMILES OC(=O)c1cccc(NC(=O)c2n[nH]c(n2)-n2cnnc2)c1

InChI Key InChIKey=JGTCMCVJBJKSBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587881   

TargetCyclic GMP-AMP synthase(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50587881(CHEMBL5173649)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of N-terminal 6XHis-SUMO2 fused full length human cGAS (1 to 522 residues) expressed in human THP-1 cells transfected with HT-DNA incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed