BDBM50587662 CHEMBL1915474

SMILES Oc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCNC(=O)c2ccccc2)n1

InChI Key InChIKey=LFYPPNJBUXJRMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587662   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587662(CHEMBL1915474)
Affinity DataIC50: 0.978nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587662(CHEMBL1915474)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of RAF1 (unknown origin) incubated for 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed