BDBM50587506 CHEMBL5081630

SMILES Oc1ccccc1\C=N\c1ccc2c(cc(=O)oc2c1)C(F)(F)F

InChI Key InChIKey=LDLCEBCEYWLLCV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587506   

TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 1.66E+3nMAssay Description:Binding affinity to GST-tagged AR ligand binding domain (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP assessed as decrease in PSA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed