BDBM50587486 CHEMBL5092161

SMILES CCc1nnc(s1)-c1cc2c(nc1C)[nH]c1c(cccc21)C1CC1

InChI Key InChIKey=WUIJYNFEAQTSHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587486   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587486(CHEMBL5092161)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587486(CHEMBL5092161)
Affinity DataIC50: 6.62E+3nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed