BDBM50587446 CHEMBL5092292

SMILES FC(F)(F)COc1ccc(cc1)-c1nnc(Nc2ccccc2)s1

InChI Key InChIKey=KFWAGFVQOCVNQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587446   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587446(CHEMBL5092292)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587446(CHEMBL5092292)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587446(CHEMBL5092292)
Affinity DataIC50: 7.37E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed