BDBM50587363 CHEMBL5081562

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CSCC#CC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)NC([C@@H](C)CC)C(=O)N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(N)=O

InChI Key InChIKey=WRHLPNHYIFLRMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587363   

TargetGTPase KRas(Human)
Cambridge University

Curated by ChEMBL
LigandPNGBDBM50587363(CHEMBL5081562)
Affinity DataIC50: 23nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to biotinylated-KRAS G12V mutant (unknown origin) measured after 60 mins by HTRF comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed