BDBM50587320 CHEMBL5079522

SMILES CN1CCN(CC(=O)Nc2c(C)[nH]c(\C=C3/C(=O)Nc4cc(NC(=O)Nc5cc(on5)C(C)(C)C)ccc34)c2C)CC1

InChI Key InChIKey=YLKFFTVAKILRBN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587320   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587320(CHEMBL5079522)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of CSF1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587320(CHEMBL5079522)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to CSF-1R in C57BL/6 mouse BMDM cells assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed