BDBM50587268 CHEMBL5087770

SMILES ONC(=O)c1ccc(cc1)N1CCCc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc12

InChI Key InChIKey=WCMRWJOERMNVPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587268   

TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50587268(CHEMBL5087770)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells using RHK-K(Ac)-AMC as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50587268(CHEMBL5087770)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed