BDBM50587012 CHEMBL5083197

SMILES C[C@H](Oc1cc(NC(=O)C(\C#N)=C(\C)O)c(F)cc1C(=O)Nc1c(Br)cccc1Br)C(F)(F)F

InChI Key InChIKey=NBFUQHTVLPTWOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587012   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50587012(CHEMBL5083197)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human DHODH using dihydroorotate substrate preincubated for 30 mins followed by substrate addition by DCIP based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed