BDBM50586999 CHEMBL5083113

SMILES CC(C)Oc1cc(NC(=O)C(\C#N)=C(\C)O)c(F)cc1C(=O)Nc1c(F)cccc1F

InChI Key InChIKey=AWNTZIVFMQTYTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586999   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50586999(CHEMBL5083113)
Affinity DataIC50: 36nMAssay Description:Inhibition of human DHODH using dihydroorotate substrate preincubated for 30 mins followed by substrate addition by DCIP based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed