BDBM50586292 CHEMBL5086221

SMILES Cc1cnc(Nc2ccnn2C)nc1-c1ccc2C(=O)N(CCc2c1)[C@H](CO)c1cccc(Cl)c1

InChI Key InChIKey=JKFLWJPNOQTXIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586292   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586292(CHEMBL5086221)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of ERK2 (unknown origin) measured after 2 hr by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed