BDBM50586170 CHEMBL5079867

SMILES COc1cc(C)[nH]c(=O)c1CN1CCN(C)c2c(Cl)cc(c(Cl)c2C1=O)-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=VXKLJLVDSREJRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586170   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Tri-Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50586170(CHEMBL5079867)
Affinity DataIC50: 220nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed