BDBM50586162 CHEMBL5079717

SMILES COc1cc(C)[nH]c(=O)c1CN1CCN(C)c2ccc(-c3c(C)noc3C)c(Cl)c2C1=O

InChI Key InChIKey=NGORJRFCJNAQJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586162   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Tri-Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50586162(CHEMBL5079717)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed