BDBM50586161 CHEMBL5085040

SMILES CCN1CCN(Cc2c(OC)cc(C)[nH]c2=O)C(=O)c2c(Cl)c(cc(Cl)c12)-c1c(C)noc1C

InChI Key InChIKey=AAKPSCQRIAUVSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586161   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Tri-Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50586161(CHEMBL5085040)
Affinity DataIC50: 33nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed