BDBM50585958 CHEMBL5090017

SMILES COc1ccc(N2CCN(CCn3c4nc(N)nc(-c5ccc(C)o5)c4ncc3=O)[C@@H](C)C2)c(F)c1

InChI Key InChIKey=QLDKSNSJQOSBLD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585958   

TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585958(CHEMBL5090017)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human A2aR expressed in HEK293 cells assessed as reduction in NECA-induced cAMP production incubated for 20 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585958(CHEMBL5090017)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human A2aR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 60 mins by ultra LANCE cAMP detect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585958(CHEMBL5090017)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human A2aR expressed in HEK293 cells assessed as reduction in NECA-induced cAMP production incubated for 20 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585958(CHEMBL5090017)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human A2aR expressed in HEK293 cells assessed as reduction in NECA-induced cAMP production incubated for 20 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed