BDBM50585931 CHEMBL4598256

SMILES CC1=C(C(=O)Oc2c1ccc(c2)OCC3CCN(CC3)Cc4ccccc4)C

InChI Key InChIKey=MWFBGTXYOJLQIW-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585931   

TargetAmine oxidase [flavin-containing] A(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585931(CHEMBL4598256)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in supersomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585931(CHEMBL4598256)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant MAO-B expressed in supersomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585931(CHEMBL4598256)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant AChE by Ellman's spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585931(CHEMBL4598256)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of horse serum BChE by Ellman's spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed