BDBM50585924 CHEMBL5072382

SMILES Cc1c(C)c(=O)oc2cc(OCC3CCCN(CCCC(F)F)C3)ccc12

InChI Key InChIKey=KUHCABBCAHJPQR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585924   

TargetAmine oxidase [flavin-containing] A(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585924(CHEMBL5072382)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in supersomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585924(CHEMBL5072382)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant MAO-B expressed in supersomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585924(CHEMBL5072382)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant AChE by Ellman's spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585924(CHEMBL5072382)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculosomes by fluorescent homogenous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed