BDBM50585805 CHEMBL5093818

SMILES CN(CCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)C1CCC(F)(F)CC1

InChI Key InChIKey=OSKSLFQSLKWAIH-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50585805   

TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 810nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed