BDBM50585788 CHEMBL5070958

SMILES NCCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12

InChI Key InChIKey=AJBIIZLEMNVANQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50585788   

TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed