BDBM50585752 CHEMBL5093797

SMILES OCc1ccn(n1)-c1ccc(Nc2cc3nc(ccc3cn2)N(CC(O)=O)C2CCNCC2)c(F)c1

InChI Key InChIKey=BZAMUGWDAXKCEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585752   

TargetCyclin-dependent kinase 5 activator 1(Human)
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585752(CHEMBL5093797)
Affinity DataIC50: 26nMAssay Description:Inhibition of full length N-terminal GST fused human CDK5(1 to 292 residues)/ p25 (99 to 307 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585752(CHEMBL5093797)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of full length N-terminal GST tagged human CDK2(1 to 298 residues)/CyclinA2 (1 to 432 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed