BDBM50585707 CHEMBL5091221::US12281080, SCCP 6336

SMILES CN(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc2cc(CCNc3ccnc4ccc(cc34)C#N)ccc2c1

InChI Key InChIKey=WSHKPIHTYDQNDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585707   

TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585707(CHEMBL5091221 | US12281080, SCCP 6336)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585707(CHEMBL5091221 | US12281080, SCCP 6336)
Affinity DataIC50: 9.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent