BDBM50585678 CHEMBL5093228

SMILES C\C(N)=N/C(=N/S(=O)(=O)N1CCCCC1)/N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=YYCNIKZOPYKSRX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585678   

TargetCannabinoid receptor 1(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50585678(CHEMBL5093228)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CB1R expressed in CHO-K1 cell membranes assessed as stimulation of [35S]-GTPgammaS binding by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50585678(CHEMBL5093228)
Affinity DataIC50: 2nMAssay Description:Inverse agonist activity at human CB1R expressed in CHO-K1 cell membrane assessed as increase in [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50585678(CHEMBL5093228)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]- CP55940 from human CB1R expressed in CHO-K1 cells membrane by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50585678(CHEMBL5093228)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]- CP55940 from human CB2R expressed in CHO-K1 cells membrane by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed