BDBM50585538 CHEMBL5087579

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](CCCCNC(=O)OC[C@H]2O[C@@H](n3ccc(N)nc3=O)C(F)(F)[C@@H]2O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O

InChI Key InChIKey=JEFQWMUHPVPCQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585538   

TargetIntegrin alpha-V/beta-3(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50585538(CHEMBL5087579)
Affinity DataIC50: 210nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human WM 266-4 cells preincubated for 30 mins followed by VN sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50585538(CHEMBL5087579)
Affinity DataIC50: 120nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human A549 cells preincubated for 30 mins followed by VN substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed