BDBM50585533 CHEMBL5094835

SMILES c1c(cnc(n1)NC2(CC2)c3cncnc3)C(=O)N4CCC[C@H](C4)C#N

InChI Key InChIKey=CDTXEVWHMGPGKZ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585533   

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585533(CHEMBL5094835)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBiotinidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585533(CHEMBL5094835)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed