BDBM505855 (S)-8-chloro-6-(((1-cyclopropyl-1H-1,2,3- triazol-4-yl)(isoquinolin-8-yl)methyl)amino)- 4-(neopentylamino)quinoline-3-carbonitrile::US11066414, Compound 504

SMILES CC(C)(C)CNc1c(cnc2c(Cl)cc(N[C@H](C3=CN(NN3)C3CC3)c3cccc4ccncc34)cc12)C#N

InChI Key InChIKey=CREUGEMMASDNIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505855   

TargetEpidermal growth factor receptor(Human)
Gilead Sciences

US Patent
LigandPNGBDBM505855((S)-8-chloro-6-(((1-cyclopropyl-1H-1,2,3- triazol-...)
Affinity DataIC50: 1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2021
Entry Details
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