BDBM50585330 CHEMBL5088136

SMILES CNCCN(CCO)c1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1

InChI Key InChIKey=MTSXSUVIZMYWTK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585330   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585330(CHEMBL5088136)
Affinity DataIC50: 148nMAssay Description:Inhibition of human PI3Kalpha by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585330(CHEMBL5088136)
Affinity DataIC50: 627nMAssay Description:Inhibition of human PI3Kbeta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585330(CHEMBL5088136)
Affinity DataIC50: 869nMAssay Description:Inhibition of human PI3Kgamma by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585330(CHEMBL5088136)
Affinity DataIC50: 47nMAssay Description:Inhibition of human PI3Kdelta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed