BDBM50585324 CHEMBL5077891

SMILES NOCCOCCOCCOCCNc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1

InChI Key InChIKey=ZNVPUJRXUHDWHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585324   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585324(CHEMBL5077891)
Affinity DataIC50: 89nMAssay Description:Inhibition of human PI3Kalpha by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585324(CHEMBL5077891)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human PI3Kbeta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585324(CHEMBL5077891)
Affinity DataIC50: 502nMAssay Description:Inhibition of human PI3Kgamma by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50585324(CHEMBL5077891)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PI3Kdelta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed