BDBM50585194 CHEMBL5087006

SMILES NS(=O)(=O)c1ccc(CNc2ccnc(Nc3cccc(NC(=O)N4CCCC4)c3)n2)cc1

InChI Key InChIKey=HMJLKNDKEHFXHG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50585194   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 305nMAssay Description:Inhibition of recombinant human FMS (538 to end residues) using KKKSPGEYVNIEFG as substrate measured after 40 mins in presence of [gamma33P]ATP by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 33nMAssay Description:Inhibition of human TYK2 (875 to end residues) using GGMEDIYFEFMGGKKK as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NanoLuc-fused CSF1R (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585194(CHEMBL5087006)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NanoLuc-fused TYK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed