BDBM50585078 CHEMBL5077573

SMILES Oc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCNS(=O)(=O)c2ccccc2)n1

InChI Key InChIKey=WTKVNGJHSXXEQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585078   

TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585078(CHEMBL5077573)
Affinity DataIC50: 35nMAssay Description:Inhibition of human wild type BRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585078(CHEMBL5077573)
Affinity DataIC50: 19nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585078(CHEMBL5077573)
Affinity DataIC50: 21nMAssay Description:Inhibition of human wild type CRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed