BDBM50585040 CHEMBL5077710

SMILES [H][C@@]12[C@@H](C)OC(=O)[C@@]11CNC[C@H]1[C@H](C)[C@@H](C)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N

InChI Key InChIKey=RQGVWWWHJXWMBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585040   

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50585040(CHEMBL5077710)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human PAR-1 expressed in HEK293 cells assessed as reduction in TRAP induced calcium signal at 3 uM by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50585040(CHEMBL5077710)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed