BDBM50585037 CHEMBL5085562

SMILES [H][C@@]12[C@@H](C)OC(=O)[C@]1(O)CC(F)(F)[C@@H](C)[C@@H]2\C=C\c1ccc(cn1)-c1cccc(C)c1C#N

InChI Key InChIKey=HYZZUHLFTHINHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585037   

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50585037(CHEMBL5085562)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human PAR-1 expressed in HEK293 cells assessed as reduction in TRAP induced calcium signal at 3 uM by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50585037(CHEMBL5085562)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50585037(CHEMBL5085562)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cells at 60 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed