BDBM50585018 CHEMBL5075422

SMILES Cn1cc(ccc1=O)-c1cnc(N)n2nc(nc12)-c1ccco1

InChI Key InChIKey=REBSCEKUSAWQBZ-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50585018   

TargetAdenosine receptor A1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human recombinant adenosine A1 receptor transfected in HEK293 cells co-transfected with Galpha15/16 assessed as intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human recombinant adenosine A2A receptor transfected in HEK293 cells co-transfected with Galpha15/16 assessed as intracellular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataIC50: 479nMAssay Description:Antagonist activity at human recombinant adenosine A2B receptor transfected in HEK293 cells co-transfected with Galpha15/16 assessed as intracellular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataIC50: 2.02E+3nMAssay Description:Antagonist activity at human recombinant adenosine A3 receptor transfected in HEK293 cells co-transfected with Galpha15/16 assessed as intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H] ZM241385 from human recombinant A2A adenosine receptor expressed in HeLa cells incubated for 30 mins by radioligand binding comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataKi:  24nMAssay Description:Displacement of [3H] DPCPX from human recombinant A1 adenosine receptor expressed in CHO cells incubated for 60 mins by radioligand binding competiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataKi:  491nMAssay Description:Displacement of [3H] DPCPX from human recombinant A2B adenosine receptor expressed in HEK293 cells incubated for 30 mins by radioligand binding compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50585018(CHEMBL5075422)
Affinity DataKi:  8.79E+3nMAssay Description:Displacement of [3H] NECA from human recombinant A3 receptor expressed in HeLa cells incubated for 180 mins by radioligand binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed