BDBM50585016 CHEMBL5085606

SMILES [H][C@@]12CC[C@@](O)(C#Cc3ccc(-c4ccc(cc4)N(c4ccccc4)c4ccccc4)c4nsnc34)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]

InChI Key InChIKey=IUXDSWZYLRTQNC-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585016   

TargetEstrogen receptor(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585016(CHEMBL5085606)
Affinity DataEC50:  1.70E+4nMAssay Description:Induction of degradation of human ERalpha in MCF7 cells irradiated with 460 light for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585016(CHEMBL5085606)
Affinity DataEC50:  500nMAssay Description:Induction of degradation of human ERalpha in MCF7 cells irradiated with 460 light for 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585016(CHEMBL5085606)
Affinity DataKi:  73nMAssay Description:Binding affinity to human ERalpha by competitive fluorometric receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed