BDBM50584715 CHEMBL5092454

SMILES Cc1cc(NC(=O)Nc2cc(nn2-c2cccc(F)c2)C(C)(C)C)ccc1Nc1ncnc2NC(=O)C(C)(C)Oc12

InChI Key InChIKey=GEGAHMIBPFSFDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584715   

TargetBDNF/NT-3 growth factors receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584715(CHEMBL5092454)
Affinity DataIC50: 14nMAssay Description:Inhibition of wild type TrkB (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584715(CHEMBL5092454)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type TrkC (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584715(CHEMBL5092454)
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type TrkA (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed