BDBM50584698 CHEMBL5088342

SMILES CC1(C)Oc2c(Nc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3)ncnc2NC1=O

InChI Key InChIKey=ZOPZPCYIDAHBGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584698   

TargetBDNF/NT-3 growth factors receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584698(CHEMBL5088342)
Affinity DataIC50: 17nMAssay Description:Inhibition of wild type TrkB (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584698(CHEMBL5088342)
Affinity DataIC50: 74nMAssay Description:Inhibition of wild type TrkC (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50584698(CHEMBL5088342)
Affinity DataIC50: 76nMAssay Description:Inhibition of wild type TrkA (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed