BDBM50584462 CHEMBL5077333

SMILES ONC(=O)\C=C\c1cnc(s1)-c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=SJVDHEBYODYANO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584462   

TargetHistone deacetylase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584462(CHEMBL5077333)
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC in human HeLa nuclear extracts using fluorometric substrate incubated for 30 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584462(CHEMBL5077333)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged HDAC3 expressed in baculovirus insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584462(CHEMBL5077333)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed