BDBM50584437 CHEMBL5075320

SMILES COc1cc(cc(OC)c1OC)-c1ncc(s1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=RHJGTOMAWYAOCO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584437   

TargetHistone deacetylase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584437(CHEMBL5075320)
Affinity DataIC50: 670nMAssay Description:Inhibition of HDAC in human HeLa nuclear extracts using fluorometric substrate incubated for 30 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584437(CHEMBL5075320)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged HDAC3 expressed in baculovirus insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50584437(CHEMBL5075320)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed