BDBM50584393 CHEMBL5085236

SMILES Cc1cc(C)cc(Nc2nccc(n2)-c2c(ncn2C2CCNCC2)-c2ccc(I)cc2)c1

InChI Key InChIKey=GHSOTOANBWUJKM-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584393   

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50584393(CHEMBL5085236)
Affinity DataIC50: 92nMAssay Description:Inhibition of BRD4 D1 (unknown origin) by competitive fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50584393(CHEMBL5085236)
Affinity DataIC50: 200nMAssay Description:Inhibition of BRD4 D1 (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50584393(CHEMBL5085236)
Affinity DataKd:  100nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed