BDBM50584384 CHEMBL5090226::US20240067625, Compound 30

SMILES Cc1cc(nn1C)C(=O)N1CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=SSGJAUSSGPIZEE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584384   

TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50584384(CHEMBL5090226 | US20240067625, Compound 30)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50584384(CHEMBL5090226 | US20240067625, Compound 30)
Affinity DataEC50:  0.0670nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent