BDBM50584380 CHEMBL5087865

SMILES CCc1ccc(cc1)N(CC1CC1)S(=O)(=O)c1ccc2OC(CC(=O)c2c1)C1CCOCC1

InChI Key InChIKey=KLRASLIFQPCBTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584380   

TargetNuclear receptor ROR-gamma(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50584380(CHEMBL5087865)
Affinity DataIC50: 10nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50584380(CHEMBL5087865)
Affinity DataIC50: 43nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) transfected in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed