BDBM50584342 CHEMBL5080953

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc2CN(C3CCOCC3)C(=O)c2c1

InChI Key InChIKey=WEAJBHADGPXYTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584342   

TargetNuclear receptor ROR-gamma(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50584342(CHEMBL5080953)
Affinity DataIC50: 105nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50584342(CHEMBL5080953)
Affinity DataIC50: 429nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) transfected in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed