BDBM50583794 CHEMBL5075493

SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC2=O)[C@@H](C)O)C(N)=O

InChI Key InChIKey=UXLTZTRGAWBLIW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50583794   

TargetCoagulation factor XII(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 331nMAssay Description:Inhibition of human factor 12a using H-D-Pro-Phe-Arg-p-nitroanilide as chromogenic substrate assessed as liberation of p-nitroaniline measured every ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 611nMAssay Description:Inhibition of human factor 12a using H-D-Pro-Phe-Arg-p-nitroanilide as chromogenic substrate assessed as liberation of p-nitroaniline in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10a using methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Urokinase-type plasminogen activator (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor 7a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583794(CHEMBL5075493)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed