BDBM50583625 CHEMBL5075729

SMILES ONC(=O)CCCCCCC(=O)N\N=C\c1ccc(cc1)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=KXWWYFKVBFUVIZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50583625   

TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 400nMAssay Description:Inhibition of full length human HDAC6 using FAM-labeled acetylated peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC1 expressed in baculovirus system using FTS as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus system using FTS as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 52nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC3 expressed in baculovirus system using FTS as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC2 expressed in baculovirus system using FTS as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50583625(CHEMBL5075729)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC8 expressed in baculovirus system using FTS as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed